| Overall: 23-8 | Home: 12-1 | Away: 7-4 | Neutral: 4-3 | PBC: 15-5 |
| Date | Day | Opponent | Time |
| Nov. 8 | Tues. | at UNC Wilmington (Exhibition) | L 74-43 Box |
| Nov. 16 | Wed. | at Queens (N.C.) | W 68-62 Box |
| Nov. 18-19 | Fri.-Sat. | at 2005 Johnson C. Smith Tournament (Charlotte, N.C.) | |
| Nov. 18 | Fri. | vs. Shaw | W 69-67 (OT) Box |
| Nov. 19 | Sat. | vs. Carson-Newman | W 75-70 Box |
| Nov. 26 | Sat. | vs. Fort Valley State (Tifton, Ga.) | L 47-46 Box |
| Nov. 30 | Wed. | Clayton College & State * | W 69-63 Box |
| Dec. 3 | Sat. | at Columbus State * | L 77-65 Box |
| Dec. 16-17 | Fri.-Sat. | 2005 Chatham Orthopaedics Holiday Classic | |
| Dec. 16 | Fri. | Presbyterian vs. Montevallo | UM 59-52 |
| AASU vs. Lenoir-Rhyne | W 66-55 Box | ||
| Dec. 17 | Sat. | Lenoir-Rhyne vs. Montevallo | UM 73-55 |
| AASU vs. Presbyterian | W 65-56 Box | ||
| Dec. 20 | Tues. | Florida Tech | W 78-71 Box |
| Dec. 30 | Fri. | at USC Aiken * | W 81-67 Box |
| Jan. 4 | Wed. | Francis Marion * | W 75-59 Box |
| Jan. 7 | Sat. | at UNC Pembroke * | W 79-60 Box |
| Jan. 11 | Wed. | Lander * | W 63-51 Box |
| Jan. 18 | Wed. | USC Upstate * | W 50-49 Box |
| Jan. 21 | Sat. | at North Georgia * | W 98-85 Box |
| Jan. 23 | Mon. | Augusta State * | L 64-58 Box |
| Jan. 25 | Wed. | at Clayton College & State * | L 66-49 Box |
| Jan. 28 | Sat. | Columbus State * | W 84-75 Box |
| Feb. 1 | Wed. | at Augusta State * | W 70-52 Box |
| Feb. 4 | Sat. | USC Aiken * | W 75-65 Box |
| Feb. 6 | Mon. | at Georgia College & State * | L 74-65 Box |
| Feb. 8 | Wed. | at Francis Marion * | W 71-63 Box |
| Feb. 11 | Sat. | UNC Pembroke * | W 85-68 Box |
| Feb. 15 | Wed. | at Lander * | W 55-45 Box |
| Feb. 20 | Mon. | Georgia College & State * | W 57-50 Box |
| Feb. 22 | Wed. | at USC Upstate * | L 76-67 Box |
| Feb. 25 | Sat. | North Georgia * | W 74-49 Box |
| Mar. 1-Mar. 5 | Wed.-Sun. | 2006 Peach Belt Conference Championships (Greenwood, S.C.) | |
| Mar. 3 | Fri. | vs. Augusta State | W 76-69 Box |
| Mar. 4 | Sat. | vs. GC&SU | W 74-72 Box |
| Mar. 5 | Sun. | vs. USC Upstate | L 73-49 Box |
| Mar. 11-14 | Sat.-Tues. | NCAA South Atlantic Regional (Richmond, Va.) | |
| Mar. 11 | Sat. | vs. Presbyterian | L 73-67 Box |
* denotes Peach
Belt Conference game
Bold denotes home game
Click on opponent's name for that school's athletic web page.