| Overall: 15-13 | Home: 9-5 | Away: 5-7 | Neutral: 1-1 | PBC: 10-10 |
| Date | Day | Opponent | Time |
| Nov. 18-19 | Fri.-Sat. | at 2005 Carson-Newman Eagle Club Classic(Jefferson City, Tenn.) | |
| Nov. 18 | Fri. | vs. Mars Hill | W 80-69 Box |
| Nov. 19 | Sat. | at Carson-Newman | W 72-61 Box |
| Nov. 22 | Tues. | at Valdosta State | L 71-49 Box |
| Nov. 30 | Wed. | Clayton College & State * | L 78-60 Box |
| Dec. 3 | Sat. | at Columbus State * | L 76-54 Box |
| Dec. 13 | Tues. | Fayetteville State | L 84-66 Box |
| Dec. 16-17 | Fri.-Sat. | 2005 Chatham Orthopaedics Holiday Classic | |
| Dec. 16 | Fri. | Carson-Newman vs. Fayetteville State | FSU 66-58 |
| AASU vs. Tusculum | W 86-84 OT Box | ||
| Dec. 17 | Sat. | Tusculum vs. Fayetteville State | TC 66-63 |
| AASU vs. Carson-Newman | W 58-53 Box | ||
| Dec. 20 | Tues. | Florida Tech | W 57-55 Box |
| Dec. 30 | Fri. | at USC Aiken * | W 75-70 Box |
| Jan. 4 | Wed. | Francis Marion * | W 64-47 Box |
| Jan. 7 | Sat. | at UNC Pembroke * | L 70-59 Box |
| Jan. 11 | Wed. | Lander * | W 68-40 Box |
| Jan. 18 | Wed. | USC Upstate * | L 60-56 Box |
| Jan. 21 | Sat. | at North Georgia | L 93-85 Box |
| Jan. 23 | Mon. | Augusta State * | L 54-47 Box |
| Jan. 25 | Wed. | at Clayton College & State * | L 78-60 Box |
| Jan. 28 | Sat. | Columbus State * | W 47-43 Box |
| Feb. 1 | Wed. | at Augusta State * | W 65-54 Box |
| Feb. 4 | Sat. | USC Aiken * | W 67-62 Box |
| Feb. 6 | Mon. | at Georgia College & State * | L 63-62 Box |
| Feb. 8 | Wed. | at Francis Marion * | L 58-56 Box |
| Feb. 11 | Sat. | UNC Pembroke * | W 58-48 Box |
| Feb. 15 | Wed. | at Lander * | W 78-64 Box |
| Feb. 20 | Mon. | Georgia College & State * | W 75-61 Box |
| Feb. 22 | Wed. | at USC Upstate * | W 73-71 Box |
| Feb. 25 | Sat. | North Georgia | L 74-61 Box |
| Mar. 1-Mar. 5 | Wed.-Sun. | 2006 Peach Belt Conference Championships (Greenwood, S.C.) | |
| March 2 | Thurs. | vs. GC&SU | L 63-60 Box |
* denotes Peach
Belt Conference game
Bold denotes home game
Click on opponent's name for that school's athletic web page.